Accelerated elimination of phenobarbital by oral activated charcoal suspensions with alkaline diuresis in an overdose patient.
نویسندگان
چکیده
منابع مشابه
Activated charcoal for acute overdose: a reappraisal.
Sometimes mistakenly characterized as a 'universal antidote,' activated charcoal (AC) is the most frequently employed method of gastrointestinal decontamination in the developed world. Typically administered as a single dose (SDAC), its tremendous surface area permits the binding of many drugs and toxins in the gastrointestinal lumen, reducing their systemic absorption. Like other decontaminati...
متن کاملA randomized clinical trial of activated charcoal for the routine management of oral drug overdose.
BACKGROUND Activated charcoal (AC) is commonly used for the routine management of oral drug overdose. AIM To determine whether the routine use of activated charcoal has an effect on patient outcomes. DESIGN Randomized controlled unblinded trial. METHODS We recruited all adult patients presenting with an oral overdose at The Canberra Hospital, excluding only transfers, late presenters, tho...
متن کاملIndications for single-dose activated charcoal administration in acute overdose.
PURPOSE OF REVIEW Gastrointestinal decontamination in overdose patients remains a controversial problem in emergency medicine. There has been a significant decrease in the use of single-dose activated charcoal (SDAC) in recent years based on little new evidence and possibly because the overall mortality in overdose patients is low. RECENT FINDINGS Human volunteer studies suggest SDAC is effec...
متن کاملPhenobarbitone elimination rate after oral charcoal.
Phenobarbitone elimination rate after oral charcoal Activated charcoal is used in treating poisoning by drugs to prevent their absorption. If given early and in a high dose (50 g) it will inhibit the absorption of over 90 % of most drugs.1 2A high proportion of many drugs with a long half life are excreted into the gut and reabsorbed. We report on the effect of activated charcoal, given orally ...
متن کاملActivated charcoal, emesis, and gastric lavage in aspirin overdose.
It is common practice to try to prevent intestinal absorption of ingested poisons. Controversy continues about the relative effectiveness of charcoal, ipecacuanha, and lavage in salicylate overdose,' but no study has yet compared all three methods. This study of simulated aspirin overdose in volunteers aimed to compare the effectiveness of gastric lavage, emesis induced by ipecacuanha, and acti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1988
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.19.779